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Role of GABAergic inhibition in hippocampal network oscillations.

Abstract:

Physiological rhythmic activity in cortical circuits relies on GABAergic inhibition to balance excitation and control spike timing. With a focus on recent experimental progress in the hippocampus, here we review the mechanisms by which synaptic inhibition can control the precise timing of spike generation, by way of effects of GABAergic events on membrane conductance ('shunting' inhibition) and membrane potential ('hyperpolarizing' inhibition). Synaptic inhibition itself can be synchronized b...

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Publication status:
Published

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Publisher copy:
10.1016/j.tins.2007.05.003

Authors


Paulsen, O More by this author
Journal:
Trends in neurosciences
Volume:
30
Issue:
7
Pages:
343-349
Publication date:
2007-07-05
DOI:
EISSN:
1878-108X
ISSN:
0166-2236
URN:
uuid:3521d636-7bc4-4e45-a8b8-6445a4b01e02
Source identifiers:
246733
Local pid:
pubs:246733

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