Controlling the processing of collagen-hydroxyapatite scaffolds for bone tissue engineering.

Conference item

Scaffolds are an important aspect of the tissue engineering approach to tissue regeneration. This study shows that it is possible to manufacture scaffolds from type I collagen with or without hydroxyapatite (HA) by critical point drying. The mean pore sizes of the scaffolds can be altered from 44 to 135 microm depending on the precise processing conditions. Such pore sizes span the range that is likely to be required for specific cells. The mechanical properties of the scaffolds have been mea...

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Authors: Wahl, D; Sachlos, E; Liu, C; Czernuszka, J

• Publication status: Published
• Journal: Journal of materials science. Materials in medicine
• Volume: 18
• Issue: 2
• Pages: 201-209
• Publication date: 2007-02-01
• Event title: 20th Conference of the European-Society-for-Biomaterials
• DOI: 10.1007/s10856-006-0682-9
• EISSN: 1573-4838
• ISSN: 0957-4530
• Keywords: Absorption; Durapatite; Biomimetic Materials; Elasticity; Materials Testing; Surface Properties; Porosity; Tissue Engineering; Bone Substitutes; Polyethylene Glycols; Extracellular Matrix; Crystallization; Particle Size; Biocompatible Materials; Collagen Type I; Desiccation; Cell Culture Techniques