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Insulin-like growth factor-i and risk of differentiated thyroid carcinoma in the European prospective investigation into cancer and nutrition.

Abstract:

BACKGROUND: Little is known about the causes of thyroid cancer, but insulin-like growth factor-I (IGF-I) might play an important role in its development due to its mitogenic and antiapoptotic properties. METHODS: This study prospectively investigated the association between serum IGF-I concentrations and risk of differentiated thyroid carcinoma in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition. The 345 incident cases of differentiated thyro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Schmidt, JA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Cancer Epidemiology Unit
Almquist, M More by this author
Franceschi, S More by this author
Rinaldi, S More by this author
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Publisher:
American Association for Cancer Research Inc.
Journal:
Cancer epidemiology, biomarkers and prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Volume:
23
Issue:
6
Pages:
976-985
Publication date:
2014-06-05
DOI:
EISSN:
1538-7755
ISSN:
1055-9965
URN:
uuid:350fcfd9-b518-40da-9e3f-b15e3fa7cb61
Source identifiers:
457793
Local pid:
pubs:457793
Language:
English

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