Coagulopathy and haemorrhage in human victims of Bothrops jararaca envenoming in Brazil.

Journal article

Thirty-four patients envenomed by Bothrops jararaca in Brazil were studied. Of these, 20 (59%) had incoagulable blood associated with local and/or systemic bleeding and 10 of the 20 were thrombocytopenic. Among 14 patients with coagulable blood, 6 (43%) had bleeding symptoms and 3 (21%) were thrombocytopenic. High levels of von Willebrand factor (vWF), plasminogen activator inhibitor type 1 (PAI-1) and tissue type plasminogen activator (t-PA) antigens were also recorded in some patients with ...

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Authors: Kamiguti, A; Cardoso, J; Theakston, R; Sano-Martins, I; Hutton, R

• Publication status: Published
• Journal: Toxicon : official journal of the International Society on Toxinology
• Volume: 29
• Issue: 8
• Pages: 961-972
• Publication date: 1991-01-01
• DOI: 10.1016/0041-0101(91)90079-7
• EISSN: 1879-3150
• ISSN: 0041-0101
• Language: English
• Keywords: Porphyrins; Blood Coagulation Disorders; Adult; von Willebrand Factor; Male; Hemorrhage; Adolescent; Aged; Snake Bites; Plasminogen Inactivators; Crotalid Venoms; Brazil; Middle Aged; Female; Child; Humans