- Abstract:
-
Gap junctions containing connexin 36 electrically couple interneurons in many brain regions and synchronize their activity. We used connexin-36 knock-out mice (Cx36(-/-)) to study the importance of electrical coupling between interneurons for spatial coding in the hippocampus and for different forms of hippocampus-dependent spatial memory. Recordings in behaving mice revealed that the spatial selectivity of hippocampal pyramidal neurons was reduced and less stable in Cx36(-/-) mice. Altered n...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1523/jneurosci.6512-10.2011
-
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- Journal:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 31
- Issue:
- 17
- Pages:
- 6542-6552
- Publication date:
- 2011-04-05
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- URN:
-
uuid:350b8a26-c275-4275-a8de-5e5e4ddb86b6
- Source identifiers:
-
135011
- Local pid:
- pubs:135011
- Copyright date:
- 2011
Journal article
Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory.
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