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Journal article

Volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytes.

Abstract:

During the differentiation cascade of growth plate chondrocytes, cells undergo as much as a 10-15-fold increase in volume. This volume increase, which occurs to different extents in growth plates growing at different rates, has been demonstrated to be the single most significant variable in understanding the quantitative aspects of the cellular kinetics of long bone growth. Our hypothesis is that this volume increase, which occurs through cell swelling by water imbibition, requires intracellu...

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Publication status:
Published

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Journal:
Bone
Volume:
30
Issue:
4
Pages:
574-581
Publication date:
2002-04-05
DOI:
EISSN:
1873-2763
ISSN:
8756-3282
URN:
uuid:3497c258-b124-439c-b44e-5c2ebec05769
Source identifiers:
348011
Local pid:
pubs:348011

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