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Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

Abstract:

We have demonstrated, using a combination of nuclear run-off and poly(A) site competition assays, that transcriptional termination occurs between the closely spaced human complement genes, C2 and Factor B, soon after the C2 poly(A) site. A comparison of the C2 termination signal with a functionally similar sequence downstream of the human alpha 2 globin gene reveals that both signals function in an orientation dependent manner, with subfragments of the whole signal displaying partial effects....

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
The EMBO journal
Volume:
10
Issue:
13
Pages:
4197-4207
Publication date:
1991-12-05
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:3496f4b3-cad9-41c8-b195-a26cf090387a
Source identifiers:
28342
Local pid:
pubs:28342

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