Journal article icon

Journal article

Migraine with aura is not linked to the FHM gene CACNA1A or the chromosomal region, 19p13.

Abstract:
Two microsatellite markers, tightly linked to CACNA1A, were genotyped in migraine with aura (MA) families to determine if this gene, which underlies the 19p13 linked forms of familial hemiplegic migraine, is also linked to MA. Two-point parametric lod and nonparametric linkage scores did not support linkage. Transmission disequilibrium testing provided no evidence for linkage of MA to CACNA1A. In a large dataset of 64 Canadian MA families, the authors did not find evidence to support an MA susceptibility gene in the region of 19p13.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1212/wnl.59.7.1099

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
Journal:
Neurology
Volume:
59
Issue:
7
Pages:
1099-1101
Publication date:
2002-10-01
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Source identifiers:
32222
Language:
English
Keywords:
Pubs id:
pubs:32222
UUID:
uuid:3495fedb-99df-4aff-9006-f75affde75d3
Local pid:
pubs:32222
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP