Journal article
Investigation of malaria susceptibility determinants in the IFNG/IL26/IL22 genomic region.
- Abstract:
-
Interferon-gamma, encoded by IFNG, is a key immunological mediator that is believed to play both a protective and a pathological role in malaria. Here, we investigate the relationship between IFNG variation and susceptibility to malaria. We began by analysing West African and European haplotype structure and patterns of linkage disequilibrium across a 100 kb genomic region encompassing IFNG and its immediate neighbours IL22 and IL26. A large case-control study of severe malaria in a West Afri...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/sj.gene.6364214
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Authors
Bibliographic Details
- Journal:
- Genes and immunity
- Volume:
- 6
- Issue:
- 4
- Pages:
- 312-318
- Publication date:
- 2005-06-05
- DOI:
- EISSN:
-
1476-5470
- ISSN:
-
1466-4879
- URN:
-
uuid:3489ce06-cc68-450e-82d6-117386c926db
- Source identifiers:
-
133488
- Local pid:
- pubs:133488
Item Description
Terms of use
- Copyright date:
- 2005
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