Journal article icon

Journal article

Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: evidence for Wagner's dual-process memory model.

Abstract:

Genetically modified mice, lacking the GluA1 AMPA receptor subunit, are impaired on spatial working memory tasks, but display normal acquisition of spatial reference memory tasks. One explanation for this dissociation is that working memory, win-shift performance engages a GluA1-dependent, non-associative, short-term memory process through which animals choose relatively novel arms in preference to relatively familiar options. In contrast, spatial reference memory, as exemplified by the Morri...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Expand authors...
Journal:
Neuropsychologia
Volume:
48
Issue:
8
Pages:
2303-2315
Publication date:
2010-07-05
DOI:
EISSN:
1873-3514
ISSN:
0028-3932
URN:
uuid:347814e7-e3b0-47cf-904e-1f97592009d0
Source identifiers:
52604
Local pid:
pubs:52604

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP