Journal article icon

Journal article

Matrix metalloproteinase-2 in a murine model of infantile-type polycystic kidney disease.

Abstract:

It was previously found that elevated levels of matrix metalloproteinase (MMP)-2 (gelatinase A) and -9 (gelatinase B) were synthesized and secreted into the medium by cultured kidney tubules derived from cystic C57BL/6J-cpk mice. To determine whether increased synthesis and secretion occur in vivo in this mouse model of polycystic kidney disease, kidney protein extracts, mRNA, and tissue sections were compared for expression and activity of MMP-2 and -9. Although both MMP were detected in tis...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Expand authors...
Journal:
Journal of the American Society of Nephrology : JASN
Volume:
10
Issue:
2
Pages:
210-217
Publication date:
1999-02-05
EISSN:
1533-3450
ISSN:
1046-6673
URN:
uuid:34780e8f-8208-4453-bb65-c2bccd0cd48c
Source identifiers:
411389
Local pid:
pubs:411389

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP