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Spironaphthoxazine switchable dyes for biological imaging

Abstract:

Recent developments in super-resolution microscopy have significantly expanded the requirements for switchable dyes, leading to demand for specially designed molecular switches. We report the synthesis and characterization of a spironaphthoxazine photochromic switch (a derivative of palatinate purple) displaying high photoconversion (85–95%) under readily accessible 405 nm light, broad absorption in the visible, and excellent fatigue resistance. The indole substituent on this spironaphthoxazi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1039/c8sc00130h

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Vargas Jentzsch, A More by this author
Osterrieth, JWM More by this author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; Weatherall Insti. of Molecular Medicine
Sazanovich, IV More by this author
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Funding agency for:
Xiong, Y
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Funding agency for:
Sezgin, E
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Funding agency for:
Sezgin, E
Wolfson Foundation More from this funder
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Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Chemical Science Journal website
Volume:
9
Issue:
11
Pages:
3029-3040
Publication date:
2018-02-20
Acceptance date:
2018-02-17
DOI:
EISSN:
2041-6539
ISSN:
2041-6520
Pubs id:
pubs:832410
URN:
uri:344f2f5d-4001-483a-aa89-d401336d17b8
UUID:
uuid:344f2f5d-4001-483a-aa89-d401336d17b8
Local pid:
pubs:832410

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