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Moderate dieting causes 5-HT2C receptor supersensitivity.

Abstract:

Dieting is a widespread behaviour in developed countries, which in predisposed individuals can lead to the development of clinical eating disorders such as bulimia nervosa and anorexia nervosa. We studied the effect of moderate dieting in healthy women on the prolactin response to the serotonin (5-HT) receptor agonist, m-chlorophenylpiperazine (mCPP), a measure of the sensitivity of post-synaptic 5-HT2C receptors. Dieting significantly increased the prolactin response to mCPP and lowered plas...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Psychological medicine
Volume:
26
Issue:
6
Pages:
1155-1159
Publication date:
1996-11-05
EISSN:
1469-8978
ISSN:
0033-2917
URN:
uuid:342bf2e7-717f-4f87-a9da-0f72274d1db3
Source identifiers:
186056
Local pid:
pubs:186056

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