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Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta 3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families

Abstract:

Previous studies have suggested that the serotonin transporter (5-HTT) gene and the γ-aminobutyric acid receptor subunit β3 (GABRB3) gene, or other genes in the 15q11-q13 region, are possibly involved in susceptibility to autism. To test this hypothesis we performed an association study on the collection of families from the International Molecular Genetic Study of Autism (IMGSA) Consortium, using the transmission disequilibrium test. Two polymorphisms in the 5-HTT gene (a functional insertio...

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Publication status:
Published

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Authors


Maestrini, E More by this author
Matthews, N More by this author
Wallace, S More by this author
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Journal:
AMERICAN JOURNAL OF MEDICAL GENETICS
Volume:
88
Issue:
5
Pages:
492-496
Publication date:
1999-10-15
DOI:
EISSN:
1552-485X
ISSN:
0148-7299
URN:
uuid:33fa816f-4940-447f-8a79-c05cb6c99239
Source identifiers:
37117
Local pid:
pubs:37117

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