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Endothelial cell repopulation after stenting determines in-stent neointima formation: effects of bare-metal vs. drug-eluting stents and genetic endothelial cell modification.

Abstract:

Aims

Understanding endothelial cell repopulation post-stenting and how this modulates in-stent restenosis is critical to improving arterial healing post-stenting. We used a novel murine stent model to investigate endothelial cell repopulation post-stenting, comparing the response of drug-eluting stents with a primary genetic modification to improve endothelial cell function.

Methods and results

Endothelial cell repopulation was... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/eurheartj/ehs240

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Human Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Human Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Human Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Human Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Human Genetics
Expand authors...
National Institute for Health Research More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
European heart journal Journal website
Volume:
34
Issue:
43
Pages:
3378-3388
Publication date:
2013-11-05
DOI:
EISSN:
1522-9645
ISSN:
0195-668X
URN:
uuid:33cc5541-63a7-4f15-9055-270ccae1c9bd
Source identifiers:
352461
Local pid:
pubs:352461

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