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Journal article

Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles.

Abstract:

Methods for the three-dimensional reconstruction of icosahedral particles, such as spherical viruses, from electron micrographs are well established. These methods take advantage of the 60-fold symmetry of the icosahedral group. Several features within these particles, however, may deviate from icosahedral symmetry. Examples include viral genomes, symmetry mismatched vertex proteins, unique DNA packaging vertices, flexible proteins, and proteins that are present at less than 100% occupancy. S...

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Publication status:
Published

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Publisher copy:
10.1016/j.jsb.2005.03.009

Authors


Briggs, JA More by this author
Huiskonen, JT More by this author
Fernando, KV More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
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Journal:
Journal of structural biology
Volume:
150
Issue:
3
Pages:
332-339
Publication date:
2005-06-05
DOI:
EISSN:
1095-8657
ISSN:
1047-8477
URN:
uuid:33b4f01f-f161-4a32-9aff-3ad91dbf8fb4
Source identifiers:
17079
Local pid:
pubs:17079

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