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Review: Diagnosis of scrub typhus

Abstract:

Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, an...

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Publisher copy:
10.4269/ajtmh.2010.09-0233

Authors


Newton, PN More by this author
Blacksell, SD More by this author
Journal:
American Journal of Tropical Medicine and Hygiene
Volume:
82
Issue:
3
Pages:
368-370
Publication date:
2010-03-05
DOI:
ISSN:
0002-9637
URN:
uuid:33b02a1e-8a6b-41a8-878b-dbc5391d0850
Source identifiers:
94584
Local pid:
pubs:94584
Language:
English

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