Journal article
Neuronal chloride regulation via KCC2 is modulated through a GABAB receptor protein complex
- Abstract:
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GABAB receptors are G-protein coupled receptors that mediate inhibitory synaptic actions through a series of downstream target proteins. It is increasingly appreciated that the GABAB receptor forms part of larger signalling complexes, which enable the receptor to mediate multiple different effects within neurons. Here we report that GABAB receptors can physically associate with the potassium-chloride cotransporter protein, KCC2, which sets the driving force for the chloride permeable ionotrop...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 2.8MB)
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- Publisher copy:
- 10.1523/JNEUROSCI.2164-16.2017
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Authors
Funding
+ Royal Society
More from this funder
Funding agency for:
Newey, S
Grant:
Dorothy Hodgkin Fellowship
Bibliographic Details
- Publisher:
- Society for Neuroscience Publisher's website
- Journal:
- Journal of Neuroscience Journal website
- Volume:
- 37
- Issue:
- 22
- Pages:
- 5447-5462
- Publication date:
- 2017-05-31
- DOI:
- ISSN:
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1529-2401
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:693458
- UUID:
-
uuid:33af7b18-65d1-4985-86f0-0ffa83bf37b4
- Local pid:
- pubs:693458
- Deposit date:
- 2017-05-16
Terms of use
- Copyright holder:
- Wright et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 Wright, Newey et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution License
Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in
anymedium providedthatthe original work is properly attributed.
- Licence:
- CC Attribution (CC BY)
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