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Journal article

A fluorous and click approach for screening potential PET probes: Evaluation of potential hypoxia biomarkers.

Abstract:

Radiopharmaceuticals for nuclear imaging are essentially targeting molecules, labeled with short-lived radionuclides (e.g., F-18 for PET). A significant drawback of radiopharmaceuticals development is the difficulty to access radiolabeled molecule libraries for initial in vitro evaluation, as radiolabeling has to be optimized for each individual molecule. The present paper discloses a method for preparing libraries of (18)F-labeled radiopharmaceuticals using both the fluorous-based (18)F-radi...

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Publication status:
Published

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Publisher copy:
10.1016/j.bmc.2011.10.084

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Bioorganic and medicinal chemistry
Volume:
20
Issue:
1
Pages:
324-329
Publication date:
2012-01-01
DOI:
EISSN:
1464-3391
ISSN:
0968-0896
Source identifiers:
216104
Language:
English
Keywords:
Pubs id:
pubs:216104
UUID:
uuid:338521ee-a22b-45cb-aa6d-4ae013370c03
Local pid:
pubs:216104
Deposit date:
2012-12-19

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