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Individual patient meta-analysis of single-dose rofecoxib in postoperative pain

Abstract:

Background: Individual patient meta-analysis to determine the analgesic efficacy and adverse effects of single-dose rofecoxib in acute postoperative pain. Methods: Individual patient information was available from 14 trials; 13 in dental and one in postsurgical pain. For each patient the percentage of maximum possible pain relief (%maxTOTPAR) was determined at different time points. The proportion of patients with at least 50% maxTOTPAR, and number-needed-to-treat (NNT) for at least 50% maxTO...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1471-2253-4-3

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Institution:
University of Oxford
Department:
Pain Research
Role:
Author
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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Role:
Author
Merck Sharp More from this funder
Oxford Pain Relief Trust More from this funder
Oxford Pain Research funds More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Anesthesiology Journal website
Volume:
4
Pages:
Article:3
Publication date:
2004-02-05
DOI:
ISSN:
1471-2253
URN:
uuid:3384f2c5-0df3-46b9-9bf7-1ee62304c7e9
Local pid:
ora:2256
Language:
English
Keywords:
Subjects:

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