Journal article
Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite.
- Abstract:
-
Bisphosphonates are now the most widely used drugs for diseases associated with increased bone resorption, such as osteoporosis. Although bisphosphonates act directly on osteoclasts, and interfere with specific biochemical processes such as protein prenylation, their ability to adsorb to bone mineral also contributes to their potency and duration of action. The aim of the present study was to compare the binding affinities for hydroxyapatite (HAP) of 6 bisphosphonates currently used clinicall...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.bone.2005.05.003
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Authors
Bibliographic Details
- Journal:
- Bone
- Volume:
- 38
- Issue:
- 5
- Pages:
- 617-627
- Publication date:
- 2006-05-01
- DOI:
- EISSN:
-
1873-2763
- ISSN:
-
8756-3282
- Source identifiers:
-
109086
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:109086
- UUID:
-
uuid:336e9034-2401-428c-ac01-94a0142df75c
- Local pid:
- pubs:109086
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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