Journal article icon

Journal article

Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission.

Abstract:

The effects of nicotine on dopamine transmission from mesostriatal dopamine neurons are central to its reinforcing properties. Only recently however, has the influence of presynaptic nicotinic receptors (nAChRs) on dopaminergic axon terminals within striatum begun to be understood. Here, rather than simply enhancing (or inhibiting) dopamine release, nAChRs perform the role of a presynaptic filter, whose influence on dopamine release probability depends on presynaptic activity in dopaminergic ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/sj.bjp.0707510

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
British journal of pharmacology
Volume:
153 Suppl 1
Issue:
SUPPL. 1
Pages:
S283-S297
Publication date:
2008-03-05
DOI:
EISSN:
1476-5381
ISSN:
0007-1188
URN:
uuid:333d6c62-5f7c-4d97-b699-af8d695a2b85
Source identifiers:
113970
Local pid:
pubs:113970

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP