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Thesis

Expression of factors within tumours to reduce immune suppression

Abstract:

Macrophages are important immune cells that play central roles in both health and disease. They display a broad phenotypic diversity, although for simplicity two distinct subtypes have been denoted ‘M1’ and ‘M2’. While this nomenclature is overly simple, it does provide a useful framework for classifying different macrophages. M1 macrophages are largely characterised by their pro-inflammatory, disease-fighting functions, whereas M2 macrophages are involved in wound healing, tissue remodell...

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Department:
University of Oxford
Role:
Author, Copyright Holder

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Department:
University of Oxford
Role:
Supervisor, Contributor
Department:
University of Oxford
Role:
Supervisor
Department:
University of Oxford
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English

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