Journal article icon

Journal article

Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries.

Abstract:

The construction of a transcriptional map for human chromosome 21 requires the generation of a specific catalogue of genes, together with corresponding mapping information. Towards this goal, we conducted a pilot study on a pool of random chromosome 21 cosmids representing 2 Mb of non-contiguous DNA. Exon-amplification and cDNA selection methods were used in combination to extract the coding content from these cosmids, and to derive expressed sequences libraries. These libraries and the sourc...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/4.8.1291

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
Expand authors...
Journal:
Human molecular genetics
Volume:
4
Issue:
8
Pages:
1291-1304
Publication date:
1995-08-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:3324fd44-0943-4513-82d5-85e66399a092
Source identifiers:
73826
Local pid:
pubs:73826

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP