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Journal article

The molecular biology of pituitary tumors: a personal perspective.

Abstract:

Oncogenes and tumor suppressor genes involved in most common cancers are not involved in the great majority of pituitary adenomas. Similarly, there is little evidence to suggest that the mutations involved in genetic syndromes associated with pituitary tumors (such as the gsp, MEN1, PKAR1A or AIP mutations) are common in sporadic tumors. A novel pituitary tumor transforming gene (PTTG, securin) has been identified which is over-expressed in most tumors--but it is unclear as to its causal role...

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Publication status:
Published

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Publisher copy:
10.1007/s11102-008-0158-7

Authors


Grossman, AB More by this author
Journal:
Pituitary
Volume:
12
Issue:
3
Pages:
265-270
Publication date:
2009
DOI:
EISSN:
1573-7403
ISSN:
1386-341X
URN:
uuid:331ea048-d058-47c6-9267-a2b5447fa8e9
Source identifiers:
138355
Local pid:
pubs:138355

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