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Minimizing risk of hypomethylating agent failure in patients with higher-risk MDS and practical management recommendations.

Abstract:

In Europe, azacitidine is the only hypomethylating agent approved for the treatment of patients with int-2-/high-risk myelodysplastic syndromes, offering significantly improved survival compared with conventional care. However, not all patients treated with azacitidine respond to treatment, and the vast majority of responders subsequently relapse. Currently, no standard care regimens have been established for patients after failure of azacitidine. Here, we discuss treatment options after loss...

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Publication status:
Published

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Publisher:
Elsevier
Journal:
Leukemia research
Volume:
38
Issue:
12
Pages:
1381-1391
Publication date:
2014-09-01
DOI:
EISSN:
1873-5835
ISSN:
0145-2126
Source identifiers:
493462
Language:
English
Keywords:
Pubs id:
pubs:493462
UUID:
uuid:330a88d2-069a-4497-999c-97100ab85d74
Local pid:
pubs:493462
Deposit date:
2015-01-06

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