Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis.
BACKGROUND: Oct4 is a POU-domain transcriptional factor which is essential for maintaining pluripotency in several mammalian species. The mouse, human, and bovine Oct4 orthologs display a high conservation of nucleotide sequence and genomic organization. RESULTS: Here we report an isolation of a common vole (Microtus rossiaemeridionalis) Oct4 ortholog. Organization and exon-intron structure of vole Oct4 gene are similar to the gene organization in other mammalian species. It consists of five ...Expand abstract
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- Copyright 2008 Medvedev et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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