- Abstract:
-
Recent studies suggest that natural killer T (NKT) cells play a role in early antiviral pathogenesis and are rapidly depleted in chronic human immunodeficiency virus type 1 (HIV-1) clade B infection. We aimed to characterize the phenotypic and functional characteristics of NKT cells in HIV-1 clade C-infected Africans at different stages of HIV-1 disease. NKT cell frequencies, subsets, and ex vivo effector functions were assessed using multiparametric flow cytometry in a cross-sectional analys...
Expand abstract - Publisher copy:
- 10.1089/aid.2010.0237
-
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- Journal:
- AIDS research and human retroviruses
- Volume:
- 27
- Issue:
- 5
- Pages:
- 501-509
- Publication date:
- 2011-05-05
- DOI:
- EISSN:
-
1931-8405
- ISSN:
-
0889-2229
- URN:
-
uuid:32ffe15a-feb2-480f-b144-667e31531244
- Source identifiers:
-
191279
- Local pid:
- pubs:191279
- Copyright date:
- 2011
Journal article
Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection.
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