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Assessing correlations between the spatial distribution of the dose to the rectal wall and late rectal toxicity after prostate radiotherapy: an analysis of data from the MRC RT01 trial (ISRCTN 47772397).

Abstract:

Many studies have been performed to assess correlations between measures derived from dose-volume histograms and late rectal toxicities for radiotherapy of prostate cancer. The purpose of this study was to quantify correlations between measures describing the shape and location of the dose distribution and different outcomes. The dose to the rectal wall was projected on a two-dimensional map. In order to characterize the dose distribution, its centre of mass, longitudinal and lateral extent, ...

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Publisher copy:
10.1088/0031-9155/54/21/006

Authors


Buettner, F More by this author
Gulliford, SL More by this author
Dearnaley, DP More by this author
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Journal:
Physics in medicine and biology
Volume:
54
Issue:
21
Pages:
6535-6548
Publication date:
2009-11-05
DOI:
EISSN:
1361-6560
ISSN:
0031-9155
URN:
uuid:32ed8546-5577-479f-87e3-9a8189fc569b
Source identifiers:
312461
Local pid:
pubs:312461

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