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The role of current product release criteria for identification of human islet preparations suitable for clinical transplantation.

Abstract:

BACKGROUND: Alloimmunity, autoimmunity, and nonspecific inflammation are known to be potential determinants for long-term islet survival and insulin independence. Sufficient islet mass is a key determinant. But islet engraftment and posttransplant survival may also depend on functional characteristics of the graft. This study investigated the significance of current product release criteria for the transplantation outcome. METHODS: Fourty five consecutive transplanted human islet preparations...

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Authors


Eckhard, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
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Journal:
Transplantation proceedings
Volume:
36
Issue:
5
Pages:
1528-1531
Publication date:
2004-06-05
DOI:
EISSN:
1873-2623
ISSN:
0041-1345
URN:
uuid:32cb8abd-2b6b-421f-a29d-a49566b33b3a
Source identifiers:
255704
Local pid:
pubs:255704

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