Journal article
Dense genomic sampling identifies highways of pneumococcal recombination.
- Abstract:
-
Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of non-susceptible genomic variants. We report whole-genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4-km(2) refugee camp. This sequencing provides unprecedented resolution of the process of recombination and its impact on population evolution. Genomic recombination hotspots show remarkable consistency between lineages, indicating common selective pressures acting at certain loci, particu...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/ng.2895
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Authors
Bibliographic Details
- Journal:
- Nature genetics
- Volume:
- 46
- Issue:
- 3
- Pages:
- 305-309
- Publication date:
- 2014-03-01
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- Source identifiers:
-
449253
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:449253
- UUID:
-
uuid:32cb2abf-bf0c-4b75-9c61-4b2eb6d9df9c
- Local pid:
- pubs:449253
- Deposit date:
- 2014-05-12
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- Copyright date:
- 2014
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