- Abstract:
-
Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of non-susceptible genomic variants. We report whole-genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4-km(2) refugee camp. This sequencing provides unprecedented resolution of the process of recombination and its impact on population evolution. Genomic recombination hotspots show remarkable consistency between lineages, indicating common selective pressures acting at certain loci, particu...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/ng.2895
-
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- Journal:
- Nature genetics
- Volume:
- 46
- Issue:
- 3
- Pages:
- 305-309
- Publication date:
- 2014-03-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:32cb2abf-bf0c-4b75-9c61-4b2eb6d9df9c
- Source identifiers:
-
449253
- Local pid:
- pubs:449253
- Copyright date:
- 2014
Journal article
Dense genomic sampling identifies highways of pneumococcal recombination.
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