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Thesis

Dynamics of Shigella intracellular replication and plasmid maintenance

Abstract:

Shigella spp. are human specific bacterial pathogens that are an important cause of diarrhoeal disease worldwide. Shigella flexneri can invade into epithelial cells, and survive within the intracellular compartment. Escape from the vacuole and replication in the host cell cytosol are critical for S. flexneri virulence. However, little is known about the basis of bacterial replication inside host cells. There are significant limitations with current methods to study intracellular replicatio...

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Division:
MSD
Department:
Pathology Dunn School
Department:
University of Oxford
Role:
Author

Contributors

Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Keywords:
Subjects:
UUID:
uuid:32a74753-3a0e-4b32-8332-2ac21d4dd6c0
Deposit date:
2019-03-22

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