Journal article : Review
An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease
- Abstract:
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Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD. However, to date, there is no appropriate guidance on CKD in individuals with MAFLD. Furthermore, there has been little attention paid to the link between MAFLD and CKD in the Nephrology community.
Methods and Results: Using a Delphi-based approach, a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD.
Conclusions: This Delphi-based consensus statement provided guidance on the epidemiology, mechanisms, management and treatment of MAFLD and CKD, as well as the relationship between the severity of MAFLD and risk of CKD, which establish a framework for the early prevention and management of these two common and interconnected diseases.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 688.6KB, Terms of use)
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- Publisher copy:
- 10.21037/hbsn-22-421
Authors
- Publisher:
- AME Publishing
- Journal:
- Hepatobiliary Surgery and Nutrition More from this journal
- Volume:
- 12
- Issue:
- 3
- Pages:
- 386-403
- Place of publication:
- China
- Publication date:
- 2023-02-23
- Acceptance date:
- 2023-02-01
- DOI:
- EISSN:
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2304-389X
- ISSN:
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2304-3881
- Pmid:
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37351121
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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1472760
- Local pid:
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pubs:1472760
- Deposit date:
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2023-10-06
Terms of use
- Copyright holder:
- HepatoBiliary Surgery and Nutrition
- Copyright date:
- 2023
- Rights statement:
- © HepatoBiliary Surgery and Nutrition. All rights reserved. This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the noncommercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license).
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