- Abstract:
-
Osteogenesis imperfecta (OI) is a genetic bone pathology with prenatal onset, characterized by brittle bones in response to abnormal collagen composition. There is presently no cure for OI. We previously showed that human first trimester fetal blood mesenchymal stem cells (MSCs) transplanted into a murine OI model (oim mice) improved the phenotype. However, the clinical use of fetal MSC is constrained by their limited number and low availability. In contrast, human fetal early chorionic stem ...
Expand abstract - Publisher copy:
- 10.1089/scd.2013.0132
-
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- Journal:
- Stem cells and development
- Volume:
- 23
- Issue:
- 3
- Pages:
- 262-276
- Publication date:
- 2014-02-05
- DOI:
- EISSN:
-
1557-8534
- ISSN:
-
1547-3287
- URN:
-
uuid:3293800c-2cc4-4fe5-bd05-55ae652967c2
- Source identifiers:
-
429246
- Local pid:
- pubs:429246
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfecta.
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