Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade.

Journal article

PURPOSE: Previously human glandular kallikrein 2 (hK2) has been implicated to predict pathologically organ confined prostate cancer (PCa) in patients with stage T2 disease. Now we evaluated the usefulness of hK2, as measured by 2 entirely different immunoassay designs, to enhance the discrimination of pathologically organ from nonorgan confined clinical stage T1c PCa. MATERIALS AND METHODS: A consecutive series of pretreatment serum from 148 men with clinical stage T1c PCa was used in 2 equa...

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Authors: Haese, A; Vaisanen, V; Lilja, H; Kattan, M; Rittenhouse, H

• Journal: Journal of urology
• Volume: 173
• Issue: 3
• Pages: 752-756
• Publication date: 2005-03-01
• DOI: 10.1097/01.ju.0000152618.38747.dd
• EISSN: 1527-3792
• ISSN: 0022-5347
• Language: English
• Keywords: Tissue Kallikreins; Prostate-Specific Antigen; Predictive Value of Tests; Aged; Prostatic Neoplasms; Sensitivity and Specificity; Neoplasm Staging; Middle Aged; Humans; Adult; Reproducibility of Results; Male