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Molecular characterization of the 7q deletion in myeloid disorders.

Abstract:

Deletion of the long arm of chromosome 7 is a common karyotypic finding in myeloid disorders and in particular is found in association with secondary leukaemias. We have used restriction fragment length polymorphisms and gene dosage experiments to assess the loss or retention of sequences localized to chromosome 7q in five patients with clonal myeloid disorders and a 7q deletion. The deletion was interstitial in all cases with retention of the anonymous marker pS194 located at 7q36-qter. Thre...

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Publication status:
Published

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Authors


Abrahamson, G More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
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Journal:
British journal of haematology
Volume:
93
Issue:
1
Pages:
75-80
Publication date:
1996-04-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:32555824-9c56-4f48-a709-e9adc56cc07a
Source identifiers:
375309
Local pid:
pubs:375309

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