- Abstract:
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Extracellular vesicles (EVs) are particles secreted by a vast variety of cells and are often recognised to mimic the properties of their parent cell, as such those derived from developmental sources hold promise for the treatment of various diseases including myocardial infarction (MI). Here we review the experimental approaches taken for assessing the therapeutic efficacy of EVs for MI and find overt shortcomings regarding purity of isolated EVs, quantitation, dosing, EV labelling/uptake, ro...
Expand abstract - Publication status:
- In press
- Peer review status:
- Peer reviewed
- Files:
-
-
(, 0.0b)
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- Publisher copy:
- 10.1016/j.tcm.2020.08.003
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- Publisher:
- Elsevier Publisher's website
- Journal:
- Trends in cardiovascular medicine Journal website
- Publication date:
- 2020-08-18
- Acceptance date:
- 2020-08-14
- DOI:
- EISSN:
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1873-2615
- ISSN:
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1050-1738
- Pmid:
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32822840
- Pubs id:
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1129381
- Local pid:
- pubs:1129381
- Language:
- English
- Keywords:
- Format:
- Print-Electronic
- Copyright holder:
- Kennedy et al.
- Copyright date:
- 2020
- Rights statement:
- ©2020 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Journal article
Experimental limitations of extracellular vesicle-based therapies for the treatment of myocardial infarction
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