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Genetic polymorphism on endothelial nitric oxide synthase affects endothelial activation and inflammatory response during the acute phase of myocardial infarction.

Abstract:

OBJECTIVES: This study sought to evaluate the effect of genetic polymorphism G894T on endothelial nitric oxide synthase (eNOS); on the risk for myocardial infarction (MI); and on the release of von Willebrand factor (vWF), interleukin (IL)-6, IL-1b, and oxidized low-density lipoprotein (ox-LDL) levels during the acute phase of MI and one year after the event. BACKGROUND: Genetic polymorphism G894T on eNOS has been associated with increased cardiovascular risk. However, its role during the ac...

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Publisher copy:
10.1016/j.jacc.2005.05.072

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Journal:
Journal of the American College of Cardiology
Volume:
46
Issue:
6
Pages:
1101-1109
Publication date:
2005-09-05
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
URN:
uuid:322a0175-b12f-48e5-b95e-ad7b3618da1a
Source identifiers:
223216
Local pid:
pubs:223216

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