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Human prostate cancer cells express neuroendocrine cell markers PGP 9.5 and chromogranin A.

Abstract:

BACKGROUND: A proportion of men with prostate cancer will progress to develop metastatic disease involving the lymph-nodes and bone. To identify novel candidates associated with metastatic progression, we compared the proteomic profiles of LNCaP (lymph-node metastatic, androgen-dependant) and PC-3 (bone metastatic, androgen-independent), human prostate cancer cells. METHODS: Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE), followed by electrospray ionisation tandem mass spectrome...

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Publication status:
Published

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Publisher copy:
10.1002/pros.20654

Authors


Leiblich, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Biomedical Research Centre
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Journal:
The Prostate
Volume:
67
Issue:
16
Pages:
1761-1769
Publication date:
2007-12-05
DOI:
EISSN:
1097-0045
ISSN:
0270-4137
URN:
uuid:3221891d-4a82-4bbc-8557-5f824e82c450
Source identifiers:
120714
Local pid:
pubs:120714

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