Successful extracorporeal porcine liver perfusion for 72 hr.

Journal article

BACKGROUND: Improvements in extracorporeal perfusion technology and the production of transgenic pigs resistant to hyperacute rejection have stimulated several groups to re-explore the possibility of supporting patients in hepatic failure with extracorporeal porcine livers. The success of organ transplantation has also stimulated interest in using extracorporeal perfusion as a means of organ preservation and resuscitation of organs from marginal donors. The present study describes a method b...

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Authors: Butler, A; Rees, M; Wight, D; Casey, N; Alexander, G

• Publication status: Published
• Journal: Transplantation
• Volume: 73
• Issue: 8
• Pages: 1212-1218
• Publication date: 2002-04-01
• DOI: 10.1097/00007890-200204270-00005
• EISSN: 1534-6080
• ISSN: 0041-1337
• Language: English
• Keywords: Electrolytes; Animals; Regional Blood Flow; Factor V; Liver Circulation; Time Factors; Hemodynamics; Organ Preservation; Humans; Reference Values; Hydrogen-Ion Concentration; Complement System Proteins; Extracorporeal Circulation; Swine; Liver