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Journal article

Transcriptomic profiling facilitates classification of response to influenza challenge.

Abstract:

Despite increases in vaccination coverage, reductions in influenza-related mortality have not been observed. Better vaccines are therefore required and influenza challenge studies can be used to test the efficacy of new vaccines. However, this requires the accurate post-challenge classification of subjects by outcome, which is limited in current methods that use artificial thresholds to assign 'symptomatic' and 'asymptomatic' phenotypes. We present data from an influenza challenge study in wh...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s00109-014-1212-8

Authors


Davenport, EE More by this author
Antrobus, RD More by this author
Lillie, PJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
More from this funder
Funding agency for:
Knight, JC
NIHR Oxford Biomedical Research Centre More from this funder
Publisher:
Springer Berlin Heidelberg Publisher's website
Journal:
Journal of molecular medicine (Berlin, Germany) Journal website
Volume:
93
Issue:
1
Pages:
105-114
Publication date:
2015-01-05
DOI:
EISSN:
1432-1440
ISSN:
0946-2716
URN:
uuid:320410f2-2294-4bbe-823f-1bd073f4994b
Source identifiers:
488343
Local pid:
pubs:488343

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