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Dopaminergic control of the rat thyrotroph.

Abstract:

The established technique of dynamic perfusion of dispersed rat anterior pituitary cells was used to investigate the role of dopamine in the release of thyroid-stimulating hormone (TSH). The basal release of TSH was 124 +/- 22 ng/ml (mean +/- SEM) and this remained unchanged in the presence of dopamine (5 X 10(-6) M), while basal prolactin release was suppressed to 50% of control values. Perfusion with thyrotrophin-releasing hormone (TRH) in doses between 1.4 X 10(-10) and 22.4 X 10(-10) M pr...

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Publication status:
Published

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Publisher copy:
10.1159/000123448

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Besser, GM More by this author
Journal:
Neuroendocrinology
Volume:
36
Issue:
2
Pages:
125-129
Publication date:
1983-02-05
DOI:
EISSN:
1423-0194
ISSN:
0028-3835
URN:
uuid:31ea03fc-4af9-40ca-b651-799313705825
Source identifiers:
138517
Local pid:
pubs:138517

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