Biphasic decay of cell-associated HIV-1 DNA in HIV-1-infected children on antiretroviral therapy.

De Rossi, A; Walker, AS; De Forni, D; Gibb, DM

Abstract:

Cell-associated HIV-1 DNA was quantified in 33 HIV-1-infected children followed for 96 weeks after the initiation of antiretroviral therapy. HIV-1 DNA decay was biphasic, being 10-fold more rapid during the first 4 weeks, and was inversely associated with the baseline plasma HIV-1-RNA level, but unrelated to HIV-1-RNA suppression. HIV-1 DNA decay per absolute CD4 cell number was lower than per 106 CD4 cells, suggesting an ongoing infection of newly produced CD4 cells, despite HIV-1 suppression in plasma.

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APA Style

De Rossi, A., Walker, A. S., De Forni, D., & Gibb, D. M. (2002). Biphasic decay of cell-associated HIV-1 DNA in HIV-1-infected children on antiretroviral therapy. AIDS (London, England), 16(14), 1961–1963.

MLA Style

De Rossi, A., et al. “Biphasic Decay of Cell-Associated HIV-1 DNA in HIV-1-Infected Children on Antiretroviral Therapy.” AIDS (London, England), vol. 16, no. 14, 2002, pp. 1961–63.

Chicago Style

De Rossi, A, AS Walker, D De Forni, and DM Gibb. 2002. “Biphasic Decay of Cell-Associated HIV-1 DNA in HIV-1-Infected Children on Antiretroviral Therapy.” AIDS (London, England) 16 (14): 1961–63.
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