Journal article
Biphasic decay of cell-associated HIV-1 DNA in HIV-1-infected children on antiretroviral therapy.
- Abstract:
- Cell-associated HIV-1 DNA was quantified in 33 HIV-1-infected children followed for 96 weeks after the initiation of antiretroviral therapy. HIV-1 DNA decay was biphasic, being 10-fold more rapid during the first 4 weeks, and was inversely associated with the baseline plasma HIV-1-RNA level, but unrelated to HIV-1-RNA suppression. HIV-1 DNA decay per absolute CD4 cell number was lower than per 106 CD4 cells, suggesting an ongoing infection of newly produced CD4 cells, despite HIV-1 suppression in plasma.
- Publication status:
- Published
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- Publisher copy:
- 10.1097/00002030-200209270-00015
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Authors
Bibliographic Details
- Journal:
- AIDS (London, England)
- Volume:
- 16
- Issue:
- 14
- Pages:
- 1961-1963
- Publication date:
- 2002-09-01
- DOI:
- EISSN:
-
1473-5571
- ISSN:
-
0269-9370
- Source identifiers:
-
422944
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:422944
- UUID:
-
uuid:31e7a74a-9896-412b-85d6-37bc5ce25769
- Local pid:
- pubs:422944
- Deposit date:
- 2014-02-08
Terms of use
- Copyright date:
- 2002
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