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Is higher viral load in the upper respiratory tract associated with severe pneumonia? Findings from the PERCH study

Abstract:

Background. The etiologic inference of identifying a pathogen in the upper respiratory tract (URT) of children with pneumonia is unclear. To determine if viral load could provide evidence of causality of pneumonia, we compared viral load in the URT of children with World Health Organization-defined severe and very severe pneumonia and age-matched community controls. Methods. In the 9 developing country sites, nasopharyngeal/oropharyngeal swabs from children with and without pneumonia were tes...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/cid/cix148

Authors


Feikin, DR More by this author
Higdon, MM More by this author
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Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
64
Issue:
S3
Pages:
S337-S346
Publication date:
2017-05-29
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Pubs id:
pubs:827523
URN:
uri:31b66d25-e775-4d79-8738-367b127aa892
UUID:
uuid:31b66d25-e775-4d79-8738-367b127aa892
Local pid:
pubs:827523

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