A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.
A clear understanding of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis is required to accelerate the development of rapid drug susceptibility testing methods based on genetic sequence.
Raw genotype–phenotype correlation data were extracted as part of a comprehensive systematic review to develop a standardised analytical approach for interpreting resistance associated mutations for rifampicin, isoniazid, ofloxacin/levofloxacin, moxifloxacin, amikacin,...Expand abstract
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- European Respiratory Society
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- Copyright ©ERS 2017. This ERJ Open article is open access and distributed under the terms of the Creative Commons Attribution Licence 4.0.
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