Journal article
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
- Abstract:
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Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam. Replication of the most significantly associated markers was carried out in an independent Vietnamese sample of 1,737 cases and 2,934 controls. SNPs at two loci showed genome-wide significant association with DSS. We identified a suscept...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 352.1KB, Terms of use)
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- Publisher copy:
- 10.1038/ng.960
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Funding
Bibliographic Details
- Publisher:
- Springer Nature
- Journal:
- Nature Genetics More from this journal
- Volume:
- 43
- Issue:
- 11
- Pages:
- 1139-1141
- Publication date:
- 2011-10-16
- Acceptance date:
- 2011-09-09
- DOI:
- EISSN:
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1546-1718
- ISSN:
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1061-4036
- Pmid:
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22001756
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:187621
- UUID:
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uuid:3182c407-2c7b-4d75-8fa9-96b7ad302b5d
- Local pid:
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pubs:187621
- Source identifiers:
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187621
- Deposit date:
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2017-06-07
Terms of use
- Copyright holder:
- Nature America
- Copyright date:
- 2011
- Notes:
- © 2011 Nature America, Inc. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/ng.960
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