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Journal article

Basal body movements as a mechanism for mitochondrial genome segregation in the trypanosome cell cycle.

Abstract:

The mitochondrial genome of Trypanosoma brucei is organized in the form of a complex catenated network of circular DNA molecules. This mass of DNA, known as the kinetoplast, is present at a unique site in the single mitochondrion, and is replicated in a discrete, periodic S phase of the cell cycle. The single-copy nature of the kinetoplast suggests that there is a mechanism ensuring segregation fidelity of replicated copies to each daughter cell. Historically, speculation regarding the nature...

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Publication status:
Published

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Publisher copy:
10.1038/352731a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Nature
Volume:
352
Issue:
6337
Pages:
731-733
Publication date:
1991-08-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:3171a105-85a4-4619-8bcc-a58faba77a31
Source identifiers:
26648
Local pid:
pubs:26648

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