Journal article icon

Journal article

Kidney disease trials for the 21st century: innovations in design and conduct

Abstract:

Compared to other specialties, nephrology has reported relatively few clinical trials, and most of these are too small to detect moderate treatment effects. Consequently, interventions that are commonly used by nephrologists have not been adequately tested and some may be ineffective or harmful. More randomized trials are urgently needed to address important clinical questions in patients with kidney disease. The use of robust surrogate markers may accelerate early-phase drug development. How...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0003-1172-8243
More by this author
Institution:
University of Oxford
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0003-4482-4418
More by this author
Institution:
University of Oxford
Department:
Nuffield Dept of Population Health
Subgroup:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0002-1179-0023
Publisher:
Nature Research Publisher's website
Journal:
Nature Reviews Nephrology Journal website
Volume:
16
Pages:
173–185
Publication date:
2019-10-31
Acceptance date:
2019-09-18
DOI:
EISSN:
1759-507X
ISSN:
1759-5061
Pubs id:
pubs:1069866
UUID:
uuid:31625f85-9706-470b-90b3-edc888e140ce
Source identifiers:
1069866
Local pid:
pubs:1069866
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP