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Calcium-permeable AMPA receptors provide a common mechanism for LTP in glutamatergic synapses of distinct hippocampal interneuron types.

Abstract:

Glutamatergic synapses on some hippocampal GABAergic interneurons exhibit activity-induced long-term potentiation (LTP). Interneuron types within the CA1 area expressing mutually exclusive molecular markers differ in LTP responses. Potentiation that depends on calcium-permeable (CP) AMPA receptors has been characterized in oriens-lacunosum moleculare (O-LM) interneurons, which express parvalbumin and somatostatin (SM). However, it is unknown how widely CP-AMPAR-dependent plasticity is express...

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Publication status:
Published

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Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
32
Issue:
19
Pages:
6511-6516
Publication date:
2012-05-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:313ad6b8-3e4c-4b47-b660-7d23707b927c
Source identifiers:
329070
Local pid:
pubs:329070

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