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Bradykinesia and impairment of EEG desynchronization in Parkinson's disease.

Abstract:

It has been suggested that the basal ganglia control the release of cortical elements from low-frequency rhythmic idling activity during voluntary movement. This hypothesis was tested by recording the local idling rhythms of the motor cortex, the alpha and beta rhythms, in 12 untreated and treated patients with Parkinson's disease as they moved a wrist. Recordings were made after overnight withdrawal of medication and again 1 hr after levodopa. The treatment-related attenuation of the alpha a...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Marsden, CD More by this author
Journal:
Movement disorders : official journal of the Movement Disorder Society
Volume:
14
Issue:
3
Pages:
423-429
Publication date:
1999-05-05
DOI:
EISSN:
1531-8257
ISSN:
0885-3185
URN:
uuid:31315d72-dfc0-4ca8-8867-82b8b1fa78cb
Source identifiers:
368958
Local pid:
pubs:368958

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